Autoimmune hepatitis (AIH) is a chronic liver inflammation caused by the immune system attacking liver cells. It is characterized by elevated gamma globulin levels and specific autoantibodies. There are two main types: Type 1, more common in adults, and Type 2, more frequent in children. Type 1 involves ANA and ASMA autoantibodies, while Type 2 involves anti-LKM1 antibodies.
Symptoms include fatigue, joint pain, and jaundice. AIH is linked to other autoimmune disorders and often responds to corticosteroid treatment. Diagnosis involves clinical features, blood tests, and autoantibody detection. The disease's association with other autoimmune conditions suggests a genetic and environmental interplay in its development (Eilard et al., 2025).
Clinical Trials
This is a list of upcoming or ongoing clinical trials that are actively recruiting and have been listed or updated in the last two weeks: